Biotin and derivatives
Medchemexpress LLC DBCO-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 | C28H30N4O3S | 50MG
DBCO-Biotin is an alkyl chain-based PROTAC linker and click-chemistry reagent that contains a dibenzocyclooctyne (DBCO) moiety conjugated to biotin, enabling copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Supplied as a white to off-white solid, it is used for biotinylation, conjugation, and PROTAC synthesis in chemical biology applications.
- High purity of 98.5%.
- Molecular weight 502.63 g/mol.
- Molecular formula C28H30N4O3S.
- Soluble in DMSO at 31.25 mg/mL (62.17 mM).
- Store protected from light under inert gas; solid recommended at -20°C.
- Packaged as 50 mg vial.
- Enables copper-free click conjugation via SPAAC.
Medchemexpress LLC Biotin hydrazide | 66640-86-6 | MFCD00078532 | 258.34 g/mol | C10H18N4O2S | 1 ML
Biotin hydrazide is a carbonyl-reactive biotinylation reagent used to label oxidized glycans, glycoproteins, and other carbonyl-containing biomolecules. It is supplied as a solid or as a 10 mM solution in DMSO for use in conjugation, detection, and enrichment workflows.
- Reacts with carbonyl groups to form stable hydrazone linkages.
- Supplied as solid or as a 10 mM solution in DMSO for convenience.
- Enables biotin-based detection and affinity purification workflows.
- Soluble in DMSO and moderately soluble in water, with solubility data provided.
- Stable when stored under recommended temperatures for long-term use.
Medchemexpress LLC Biotin-PEG-Thiol (MW 2000) | 98.0% | 2000 (Average) | 25 MG
Biotin-PEG-Thiol (MW 2000) is an active compound that is pegylated by binding to streptavidin or antibiotin with high affinity and specificity. It can modify biomolecules, proteins, peptides, and other small molecule materials and is widely used in research concerning agent release and nano new materials.
- Functions as an active compound.
- Pegylated for high affinity and specificity binding to streptavidin or antibiotin.
- Capable of modifying biomolecules, proteins, peptides, and other small molecule materials.
- Widely used in research concerning agent release and nano new materials.
- Solid, white to off-white appearance.
- Store at -20°C, protected from light, and under nitrogen.
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light and under nitrogen.
- Soluble in DMSO at 125 mg/mL (requires ultrasonication).
Medchemexpress LLC m-PEG1-NHS ester 5g | 1027371-75-0 | 201.18 g/mol | C8H11NO5 | 5 G
m-PEG1-NHS ester is a methoxy-terminated PEG1 N-hydroxysuccinimide ester that provides an activated NHS ester for efficient coupling to primary amines. It is used as a short PEG linker in bioconjugation and PROTAC synthesis to introduce a flexible spacer and enable amide bond formation under mild conditions.
- Provides a methoxy-terminated PEG1 spacer for minimal linker length.
- Contains an active NHS ester for rapid amide coupling to primary amines.
- Suitable for PROTAC linker assembly and general bioconjugation.
- Available in multiple pack sizes for flexible scaling.